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Executive Record

Hervé Hoppenot

Chief executive: Incyte (before 2014 to 26 Jun 2025)

68commitments announced
33with a clear outcome
33met on time
100%on-time rate

Commitments are credited to the chief executive in office on the day they were announced. Where a deadline fell after the leader left, the entry is marked. Sources for each leadership change: Incyte filing.

Commitments announced under Hervé Hoppenot

Incyteannounced 31 Oct 2023 File the IND for INCB100658, a JAK2V617F-targeting small molecule inhibitor No record found31 Dec 2023
Incyteannounced 31 Oct 2023 Share additional data from ruxolitinib twice-daily combination studies with zilurgisertib and INCB57643 Met31 Dec 2023
Incyteannounced 31 Oct 2023 Initiate a Phase 3 study of povorcitinib in prurigo nodularis No record found31 Dec 2024
Incyteannounced 1 Aug 2023 Enter the clinic with auremolimab, an anti-IL-15Rβ monoclonal antibody Met31 Dec 2023
Incyteannounced 2 May 2023 Initiate the first-in-human study of INCA33989 in MF and ET Met31 Dec 2023
Incyteannounced 7 Feb 2023 Report final results from the Phase 3 trial of parsaclisib as an add-on to ruxolitinib No record found31 Dec 2023
Incyteannounced 7 Feb 2023 Initiate Phase 1/1b trial of INCB99280 with adagrasib No record found31 Dec 2023
Incyteannounced 7 Feb 2023 Present updated data for zilurgisertib combined with ruxolitinib in myelofibrosis Met31 Dec 2023
Incyteannounced 7 Feb 2023 Begin clinical trials of INCA33989 (mCALR antibody) No record found31 Dec 2023
Incyteannounced 7 Feb 2023 Present updated data for oral PD-L1 programme INCB99280 and INCB99318 No record found31 Dec 2023
Incyteannounced 7 Feb 2023 Report Phase 2 results for povorcitinib in vitiligo and prurigo nodularis Met31 Dec 2023
Incyteannounced 1 Nov 2022 Begin clinical development of auremolimab No record found31 Dec 2023
Incyteannounced 2 Aug 2022 Initiate a Phase 3 study of povorcitinib in hidradenitis suppurativa Met31 Dec 2022
Incyteannounced 3 Aug 2021 Initiate a Phase 3 trial of parsaclisib in autoimmune hemolytic anemia No record found31 Dec 2021
Incyteannounced 3 Aug 2021 Submit a regulatory application seeking approval of ruxolitinib cream in vitiligo No record found31 Dec 2021
Incyteannounced 4 May 2021 Initiate pivotal trials for tafasitamab and LIMBER programs No record found31 Dec 2021
Incyteannounced 4 May 2021 Start the topMIND proof-of-concept trial of tafasitamab plus parsaclisib No record found31 Dec 2021
Incyteannounced 9 Feb 2021 Submit a new drug application for parsaclisib in relapsed or refractory lymphoma to the FDA Met31 Dec 2021
Incyteannounced 5 Nov 2020 Report topline results from the Phase 3 RUXCOVID study Met31 Dec 2020
Incyteannounced 4 Aug 2020 Submit a New Drug Application for ruxolitinib cream Met31 Dec 2020
Incyteannounced 5 May 2020 Report results of the Phase 3 REACH 3 trial in chronic GVHD Met31 Dec 2020
Incyteannounced 13 Feb 2020 Submit NDA for ruxolitinib cream in atopic dermatitis to regulators Met31 Dec 2020
Incyteannounced 29 Oct 2019 Report initial results from the TRuE-AD Phase 3 program of ruxolitinib cream in atopic dermatitis Met30 Jun 2020
Incyteannounced 29 Oct 2019 Report initial results from the TRuE-V Phase 3 program of ruxolitinib cream in vitiligo Met31 Dec 2021
Incyteannounced 30 Jul 2019 Complete enrollment in the continuous dosing cohort of the pemigatinib bladder cancer Phase 2 trial No record found31 Dec 2019
Incyteannounced 30 Jul 2019 Begin Phase 3 development of ruxolitinib cream in patients with vitiligo Met31 Dec 2019
Incyteannounced 14 Feb 2019 Submit NDA seeking approval of pemigatinib for second-line FGFR2 translocated cholangiocarcinoma Met30 Sep 2019
Incyteannounced 14 Feb 2019 Initiate pivotal tumor-agnostic trial of pemigatinib in FGF/FGFR driver-activated solid tumors No record found31 Dec 2019
Incyteannounced 14 Feb 2019 Report Phase 3 data for ruxolitinib cream in atopic dermatitis Met31 Dec 2020
Incyteannounced 30 Oct 2018 Begin Phase 2 trials of INCMGA0012 in MSI-high endometrial, Merkel cell and anal cancers Met31 Dec 2018
Incyteannounced 30 Oct 2018 Begin Phase 3 GRAVITAS-309 trial of itacitinib in chronic GVHD Met30 Jun 2019
Incyteannounced 30 Oct 2018 Report Phase 2 data from ruxolitinib cream trial in vitiligo Met31 Dec 2019
Incyteannounced 30 Oct 2018 Submit a new drug application for pemigatinib in advanced cholangiocarcinoma Met31 Dec 2019
Incyteannounced 1 May 2018 Report data from the Phase 2 trial of topical ruxolitinib in atopic dermatitis Met31 Dec 2018
Incyteannounced 1 May 2018 Enter clinical trials with INCAGN2390 (TIM-3) No record found31 Dec 2018
Incyteannounced 1 May 2018 Enter clinical trials with INCAGN2385 (LAG-3) No record found31 Dec 2018
Incyteannounced 15 Feb 2018 Report initial progression-free survival results of the ECHO-301 trial of epacadostat in melanoma Met30 Jun 2018
Incyteannounced 15 Feb 2018 Enter clinical trials with INCB81776 (AXL/MER) No record found31 Dec 2018
Incyteannounced 15 Feb 2018 Report initial data from the trial of INCB54828 in cholangiocarcinoma Met31 Dec 2018
Incyteannounced 31 Oct 2017 Initiate the next wave of eight pivotal Phase 3 epacadostat trials with PD-1 antagonists No record found31 Dec 2017
Incyteannounced 31 Oct 2017 Deliver REACH1 pivotal trial results for ruxolitinib in steroid-refractory acute GVHD Met30 Jun 2018
Incyteannounced 31 Oct 2017 Deliver ECHO-301 Phase 3 data for epacadostat plus pembrolizumab in melanoma Met30 Jun 2018
Incyteannounced 31 Oct 2017 Begin Phase 3 trial of epacadostat with durvalumab in Stage III NSCLC No record found30 Jun 2018
Incyteannounced 31 Oct 2017 Submit sNDA seeking accelerated approval of ruxolitinib for steroid-refractory acute GVHD Met31 Dec 2018
Incyteannounced 27 Oct 2017 Close the MGA012 exclusive global collaboration and license agreement with MacroGenics Met31 Dec 2017
Incyteannounced 4 May 2017 Begin Phase 3 trials of epacadostat with nivolumab in NSCLC and head & neck cancer No record found31 Dec 2017
Incyteannounced 4 May 2017 Begin Phase 1/2 dose-escalation trial of INCB62079 in hepatocellular carcinoma No record found31 Dec 2017
Incyteannounced 4 May 2017 Begin the Phase 3 REACH3 trial of ruxolitinib in steroid-refractory chronic GVHD No record found31 Dec 2017
Incyteannounced 14 Feb 2017 Begin Phase 2 CITADEL-202 trial in diffuse large B cell lymphoma No record found30 Jun 2017
Incyteannounced 14 Feb 2017 Begin pivotal ruxolitinib program for essential thrombocythemia No record found31 Dec 2017
Incyteannounced 14 Feb 2017 Enter proof-of-concept clinical trials with FGFR4 inhibitor INCB62079 No record found31 Dec 2017
Incyteannounced 14 Feb 2017 Initiate new pivotal trials in at least six indications from the late-stage portfolio No record found31 Dec 2017
Incyteannounced 14 Feb 2017 Begin Phase 3 trials of epacadostat with pembrolizumab in four additional tumor types No record found31 Dec 2017
Incyteannounced 14 Feb 2017 Begin Phase 2 trial of topical ruxolitinib in vitiligo Met31 Dec 2017
Incyteannounced 14 Feb 2017 Enter global pivotal program for itacitinib in treatment-naive acute GVHD Met31 Dec 2017
Incyteannounced 14 Feb 2017 Begin REACH2 and REACH3 randomized Phase 3 trials in graft-versus-host disease No record found31 Dec 2017
Incyteannounced 21 Dec 2016 Close the collaboration and share purchase with Merus N.V Met31 Mar 2017
Incyteannounced 1 Nov 2016 Report data from the INCB39110 Phase 1/2 graft versus host disease trial No record found31 Dec 2016
Incyteannounced 9 Aug 2016 Present updated Phase 1 ECHO-202 data at the ESMO congress Met31 Oct 2016
Incyteannounced 9 Aug 2016 Start the Phase 2 trial of INCB54828 in bladder cancer No record found31 Dec 2016
Incyteannounced 9 Aug 2016 Report initial data from the proof-of-concept trial of INCB39110 in GVHD No record found31 Dec 2016
Incyteannounced 9 May 2016 Initiate the Phase 1/2 trial of INCAGN1876 (GITR) in solid tumors Met30 Jun 2016
Incyteannounced 9 May 2016 Initiate the Phase 1/2 trial of INCAGN1949 (OX40) in solid tumors Met31 Dec 2016
Incyteannounced 9 May 2016 Begin the U.S. pivotal trial of ruxolitinib for graft versus host disease No record found31 Dec 2016
Incyteannounced 11 Feb 2016 Initiate the Phase 1/2 study of INCB59872 (LSD1) in advanced malignancies No record found30 Jun 2016
Incyteannounced 11 Feb 2016 Begin the Phase 3 ECHO-301 study of epacadostat with pembrolizumab in first-line melanoma No record found30 Jun 2016
Incyteannounced 11 Feb 2016 Recruit over 600 patients into Phase 2 epacadostat expansion cohorts No record found31 Dec 2016
Incyteannounced 11 Feb 2016 Expect expansion cohorts of INCB54828 (FGFR) in genetically-defined tumor types No record found31 Dec 2016

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