Initiate the first-in-human study of INCA33989 in MF and ET
Delivered by the deadline
AI-assessed · human review in progress Found and assessed by AI from the cited sources. Shown with its evidence; it is not counted in any Kept Score until confirmed.
- Announced
- 2 May 2023
- Due
- 31 Dec 2023
- Deadline
- Met
- Late
- Not met
- Today
What the company said
“INCA33989 (mCALR) is on track for initiating first-in-human study in MF and ET in 2023.”
What we found
Evidence strength A What the grades mean
Filings consistently state a Phase 1 study of INCA033989 was initiated in July 2023, before the 2023 deadline; the exact day is not given.
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A Incyte 10-K filed 2024-02-13
“In July 2023, a Phase 1 study evaluating INCA033989 was initiated.” ✓ confirmed on the page
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A Incyte 10-Q filed 2024-07-30
“In July 2023, a Phase 1 study evaluating INCA033989 was initiated.” ✓ confirmed on the page
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A Incyte 10-Q filed 2024-07-30
“CALR mutations are responsible for disease development in approximately 25-35% of patients with MF and ET.” ✓ confirmed on the page
Market reaction: the shares moved +1.8% against the S&P 500 over the three sessions around the disclosure (12 Feb 2024 to 15 Feb 2024). What this measures
Checked 10 Oct 2026.
Commitment DNA
The structured record of this commitment. Fields the company did not state are left blank rather than guessed.
- Event type
- Clinical milestone
- Indicative materiality
- Medium rules
- Action
- Initiate
- Deliverable
- First-in-human study of INCA33989 in MF and ET
- In the company’s control
- High
- Specificity
- High
How this entry was checked
- Commitment recordedThe company's words were matched word for word against the filing.
- First checkAn AI model, Claude (Anthropic), read the company's later filings and recorded the outcome with a quoted passage.
- Second check: agreesA different AI model, Gemini (Google), re-read the evidence without being told the outcome and reached the same answer.
Not yet confirmed. Shown on the record, but it will not count in any score until it is confirmed. How verification works
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Report an error in this entry Reference: KI-C-2023-INCY-005710 · Corrections policy