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Vertex Pharmaceuticals

Complete enrollment in the interim analysis cohort of the AMPLITUDE trial of inaxaplin

Delivered by the deadline

AI-confirmed · human review in progress Independent AI checks agreed on primary SEC or regulator evidence. Records are now being reviewed by hand, starting with those our customers order.

Announced
10 Feb 2025
Due
31 Dec 2025
  • Deadline
  • Met
  • Late
  • Not met
  • Today

What the company said

“Vertex expects to complete enrollment in the interim analysis cohort in 2025”

What we found

Evidence strength A What the grades mean

Later filings state Vertex completed enrollment in the AMPLITUDE interim analysis cohort in September 2025, before the 2025 deadline.

  • A
    Vertex Pharmaceuticals 8-K filed 2026-02-12 Regulatory filing · published 12 Feb 2026 · retrieved 10 Oct 2026 · kept permanently by the SEC
    “In September, Vertex completed enrollment in the interim analysis cohort of the AMPLITUDE Phase 2/3 trial of inaxaplin in people with primary AMKD” ✓ confirmed on the page
  • A
    Vertex Pharmaceuticals 10-K filed 2026-02-13 Regulatory filing · published 13 Feb 2026 · retrieved 10 Oct 2026 · kept permanently by the SEC
    “We completed enrollment of the interim analysis cohort of AMPLITUDE in 2025” ✓ confirmed on the page
  • A
    Vertex Pharmaceuticals 8-K filed 2026-05-04 Regulatory filing · published 4 May 2026 · retrieved 10 Oct 2026 · kept permanently by the SEC
    “In the second half of 2025, Vertex completed enrollment in the interim analysis cohort of the AMPLITUDE Phase 2/3 trial of inaxaplin” ✓ confirmed on the page

Market reaction: the shares moved +4.8% against the S&P 500 over the three sessions around the disclosure (11 Feb 2026 to 17 Feb 2026). What this measures

Checked 10 Oct 2026.

Commitment DNA

The structured record of this commitment. Fields the company did not state are left blank rather than guessed.

Event type
Clinical readout
Indicative materiality
Medium rules
Action
Complete
Deliverable
Enrollment of AMPLITUDE interim analysis cohort
Language
Expected (“expects”, “plans”)
In the company’s control
Medium
Specificity
Medium

How this entry was checked

  1. Commitment recordedThe company's words were matched word for word against the filing.
  2. First checkAn AI model, Claude (Anthropic), read the company's later filings and recorded the outcome with a quoted passage.
  3. Second check: agreesA different AI model, Gemini (Google), re-read the evidence without being told the outcome and reached the same answer.

Confirmed. This outcome counts towards the company's Kept Score. How verification works

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Report an error in this entry Reference: KI-C-2025-VRTX-006548 · Corrections policy

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