Initiate Phase 1b study for Sickle Cell Disease
Delivered by the deadline
AI-confirmed · human review in progress Independent AI checks agreed on primary SEC or regulator evidence. Records are now being reviewed by hand, starting with those our customers order.
- Announced
- 20 Oct 2025
- Due
- 31 Dec 2025
- Delivered
- October 2025
- Deadline
- Met
- Late
- Not met
- Today
What the company said
“Sickle Cell Disease (SCD) – Phase 1b study initiation anticipated by end of year”
What we found
Evidence strength A What the grades mean
The company confirmed in its 2026 filings that it initiated the Phase 1b study of DISC-3405 in sickle cell disease during the fourth quarter of 2025, meeting the year-end deadline.
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A Disc Medicine, Inc. 8-K filed 2026-02-26
“initiated a Phase 1b study of DISC-3405 in sickle cell disease (SCD) in Q4 2025” ✓ confirmed on the page
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A Disc Medicine, Inc. 10-K filed 2026-02-26
“We also initiated a Phase 1b, open-label clinical trial of DISC-3405 in patients with SCD in October 2025” ✓ confirmed on the page
Market reaction: the shares moved +0.4% against the S&P 500 over the three sessions around the disclosure (25 Feb 2026 to 2 Mar 2026). What this measures
Checked 1 Oct 2026.
Commitment DNA
The structured record of this commitment. Fields the company did not state are left blank rather than guessed.
- Event type
- Clinical milestone
- Indicative materiality
- Medium rules
- Action
- Initiate
- Deliverable
- Phase 1b study for Sickle Cell Disease
- Language
- Expected (“expects”, “plans”)
- In the company’s control
- High
- Specificity
- High
How this entry was checked
- Commitment recordedThe company's words were matched word for word against the filing.
- First checkAn AI model, Gemini (Google), read the company's later filings and recorded the outcome with a quoted passage.
- Second check: agreesA different AI model, Claude (Anthropic), re-read the evidence without being told the outcome and reached the same answer.
Confirmed. This outcome counts towards the company's Kept Score. How verification works
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