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Xenon Pharmaceuticals Inc.

Initiate a Phase 2 proof-of-concept clinical trial for XEN1101 in a non-epilepsy indication

Delivered after the deadline

AI-confirmed · human review in progress Independent AI checks agreed on primary SEC or regulator evidence. Records are now being reviewed by hand, starting with those our customers order.

Announced
14 Jan 2021
Due
30 Jun 2021
Delivered
October 2021
  • Deadline
  • Met
  • Late
  • Not met
  • Today

What the company said

“Xenon expects to support the initiation of a Phase 2 proof-of-concept clinical trial examining XEN1101 in a non-epilepsy indication within the first half of 2021.”

What we found

Evidence strength A What the grades mean

The company committed to initiating the trial in the first half of 2021, but filings confirm that patient enrollment for the trial did not begin until October 2021.

  • A
    Xenon Pharmaceuticals Inc. 10-Q filed 2021-11-10 Regulatory filing · published 10 Nov 2021 · retrieved 24 Oct 2026 · kept permanently by the SEC · fingerprint d99b970fcbce
    “a Phase 2 proof-of-concept clinical trial examining XEN1101 in major depressive disorder and anhedonia is being conducted in partnership with academic collaborators at the Icahn School of Medicine at Mount Sinai, and patient enrollment was initiated in October 2021.” ✓ confirmed on the page

Market reaction: the shares moved -10.7% against the S&P 500 over the three sessions around the disclosure (9 Nov 2021 to 12 Nov 2021). What this measures

Checked 24 Oct 2026.

Commitment DNA

The structured record of this commitment. Fields the company did not state are left blank rather than guessed.

Event type
Clinical milestone
Indicative materiality
Medium rules
Action
Initiate
Deliverable
XEN1101 Phase 2 proof-of-concept clinical trial
Language
Expected (“expects”, “plans”)
In the company’s control
High
Specificity
High
Depends on
Regulatory

How this entry was checked

  1. Commitment recordedThe company's words were matched word for word against the filing.
  2. First checkAn AI model, Gemini (Google), read the company's later filings and recorded the outcome with a quoted passage.
  3. Second check: agreesA different AI model, Claude (Anthropic), re-read the evidence without being told the outcome and reached the same answer.

Confirmed. This outcome counts towards the company's Kept Score. How verification works

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