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Synthetic Biologics, Inc.

Begin dosing patients in the first antibiotic cohort of the SYN-004 Phase 1b/2a trial

Delivered after the deadline (14 days after the deadline)

AI-assessed · human review in progress Found and assessed by AI from the cited sources. Shown with its evidence; it is not counted in any Kept Score until confirmed.

Announced
4 Mar 2021
Due
31 Mar 2021
Delivered
14 Apr 2021
  • Deadline
  • Met
  • Late
  • Not met
  • Today

What the company said

“Expect to begin dosing patients in the first antibiotic cohort of the SYN-004 Phase 1b/2a clinical trial during Q1 2021”

What we found

Evidence strength A What the grades mean

The company announced on April 14, 2021 that the first patient in the first antibiotic cohort had been dosed, after the Q1 2021 deadline. Later filings label the dosing Q2 2021.

  • A
    Synthetic Biologics, Inc. 10-Q filed 2021-05-05 Regulatory filing · published 5 May 2021 · retrieved 27 Oct 2026 · kept permanently by the SEC
    “On April 14, 2021 we announced that enrollment has commenced and the first patient of the first antibiotic cohort of this study had been dosed.” ✓ confirmed on the page
  • A
    Synthetic Biologics, Inc. 10-Q filed 2021-08-05 Regulatory filing · published 5 Aug 2021 · retrieved 27 Oct 2026 · kept permanently by the SEC
    “Washington University began enrollment and the first patient was dosed in the first of three antibiotic cohorts for the Phase 1b/2a clinical trial of SYN-004 in adult HCT recipients (Q2 2021)” ✓ confirmed on the page
  • A
    Synthetic Biologics, Inc. 10-K filed 2022-03-16 Regulatory filing · published 16 Mar 2022 · retrieved 27 Oct 2026 · kept permanently by the SEC
    “During the first quarter of 2021, Washington University began enrollment and dosed our first patient in the first of three antibiotic cohorts” ✓ confirmed on the page

Checked 27 Oct 2026.

Commitment DNA

The structured record of this commitment. Fields the company did not state are left blank rather than guessed.

Event type
Clinical milestone
Indicative materiality
Medium rules
Action
Begin
Deliverable
Dosing of first SYN-004 Phase 1b/2a antibiotic cohort
Language
Expected (“expects”, “plans”)
In the company’s control
Medium
Specificity
High

How this entry was checked

  1. Commitment recordedThe company's words were matched word for word against the filing.
  2. First checkAn AI model, Claude (Anthropic), read the company's later filings and recorded the outcome with a quoted passage.

Not yet confirmed. Shown on the record, but it will not count in any score until it is confirmed. How verification works

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