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Silence Therapeutics plc

Report data from the single-ascending dose portion of the APOLLO study

Delivered after the deadline (40 days after the deadline)

AI-assessed · human review in progress Found and assessed by AI from the cited sources. Shown with its evidence; it is not counted in any Kept Score until confirmed.

Announced
17 Feb 2021
Due
31 Dec 2021
Delivered
9 Feb 2022
  • Deadline
  • Met
  • Late
  • Not met
  • Today

What the company said

“Silence intends to report data from the single-ascending dose portion of the study in the second half of this year.”

What we found

Evidence strength A What the grades mean

Silence reported positive topline single-ascending dose APOLLO data on 9 February 2022, after the second-half 2021 deadline.

  • A
    Silence Therapeutics plc 6-K filed 2022-02-09 Regulatory filing · published 9 Feb 2022 · retrieved 26 Oct 2026 · kept permanently by the SEC
    “Silence Therapeutics Announces Positive Topline Data in SLN360 Phase 1 Single-Ascending Dose Study in Healthy Adults with High Lipoprotein(a)” ✓ confirmed on the page
  • A
    Silence Therapeutics plc 6-K filed 2022-02-09 Regulatory filing · published 9 Feb 2022 · retrieved 26 Oct 2026 · kept permanently by the SEC
    “9 February 2022” ✓ confirmed on the page
  • A
    Silence Therapeutics plc 20-F filed 2022-03-17 Regulatory filing · published 17 Mar 2022 · retrieved 26 Oct 2026 · kept permanently by the SEC
    “In February 2022, we reported positive topline data in the single-ascending dose cohorts.” ✓ confirmed on the page

Checked 26 Oct 2026.

Commitment DNA

The structured record of this commitment. Fields the company did not state are left blank rather than guessed.

Event type
Clinical readout
Indicative materiality
Medium rules
Action
Report
Deliverable
APOLLO study single-ascending dose data
Language
Aspirational (“aims”, “intends”)
In the company’s control
High
Specificity
High

How this entry was checked

  1. Commitment recordedThe company's words were matched word for word against the filing.
  2. First checkAn AI model, Claude (Anthropic), read the company's later filings and recorded the outcome with a quoted passage.

Not yet confirmed. Shown on the record, but it will not count in any score until it is confirmed. How verification works

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Report an error in this entry Reference: KI-C-2021-SLN-024052 · Corrections policy

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