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Blueprint Medicines Corp

Initiate a Phase 1 trial of BLU-945 in patients with treatment-resistant EGFR-driven NSCLC

Delivered by the deadline

AI-confirmed · human review in progress Independent AI checks agreed on primary SEC or regulator evidence. Records are now being reviewed by hand, starting with those our customers order.

Announced
11 Jan 2021
Due
30 Jun 2021
Delivered
Q2 2021
  • Deadline
  • Met
  • Late
  • Not met
  • Today

What the company said

“Initiate a Phase 1 trial of BLU-945, a triple-mutant EGFR inhibitor, in patients with treatment-resistant EGFR-driven NSCLC in the first half of 2021”

What we found

Evidence strength A What the grades mean

The company initiated the Phase 1/2 SYMPHONY trial of BLU-945 in patients with EGFR-driven NSCLC in the second quarter of 2021, meeting the first-half 2021 deadline.

  • A
    Blueprint Medicines Corp 10-K filed 2022-02-17 Regulatory filing · published 17 Feb 2022 · retrieved 24 Oct 2026 · kept permanently by the SEC · fingerprint 9a3a67648ea3
    “Based on these preclinical data, we initiated a Phase 1/2 trial of BLU-945 in patients with EGFR-driven NSCLC, which we refer to as our SYMPHONY trial, in the second quarter of 2021.” ✓ confirmed on the page

Checked 24 Oct 2026.

Commitment DNA

The structured record of this commitment. Fields the company did not state are left blank rather than guessed.

Event type
Clinical milestone
Indicative materiality
Medium rules
Action
Initiate
Deliverable
BLU-945 Phase 1 trial
In the company’s control
High
Specificity
High

How this entry was checked

  1. Commitment recordedThe company's words were matched word for word against the filing.
  2. First checkAn AI model, Gemini (Google), read the company's later filings and recorded the outcome with a quoted passage.
  3. Second check: agreesA different AI model, Claude (Anthropic), re-read the evidence without being told the outcome and reached the same answer.

Confirmed. This outcome counts towards the company's Kept Score. How verification works

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